I am developing a method to quantify diketones, namely diacetyl and have it to the point where my peaks show good seperation but the diketone peaks are showing terrible splitting. Acetoin shows a clean single peak but any alpha diketone shows splitting. Any recommendations on what parameters to alter to help this? I am injecting with a TurboMatrix 150 ATD so there is not solvent interaction as the methanol used in spiking sample tubes is not retained by the trap I am using.