There is an option to select your impurity response in Empower 3, what exactly is the difference between "%w/w", "%Area" and "%Area against Main Component"?
My understanding is:
%Area = area of peak as a function of the Total area of all peaks in the chromatogram, both system peaks and sample peaks eg peak of impurity = 2000. Total area of every single peak in the chromatogram = 214000. % Area = (2000/214000)*100

%Area against Main component = corrected area of peak (area x RRF)/area of active*100

%w/w = I'm not entirely sure!

Can anyone clarify? Thanks.