Difference between delay and void volume

Basic questions from students; resources for projects and reports.

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Whats the difference between the void volume,dead volume,delay volume of column ?how its vary from one column to other?
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
Hi, I also have one question, which I hope you can help me with. How do you call a volume (or time) which combines the system dwell (delay) volume + column void volume?

My problem is that I don't know how to describe the time in the chromatogram when my baseline actually starts to drift in a gradient analysis (the effluent hits the detector). This is not the hold-up volume since it doesn't take the pump and mixer into account, right?

Cheers
A
Don't argue with an idiot... he will drag you to his level and beat you with experience!
As far as I know, that sum does not have an "official" name. I usually just use "tD + t0", but so long as you define your terms, you can call it whatever you want.
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
4 posts Page 1 of 1

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