inorganic mass spec

[tilly]

Please can anyone give me some pointers on the use of inorganic mass spectrometry. Like what types of analysis, ionisation techniques. I wonder if anyone has read any basic texts on this that could recommend. I've a little about seciation analysis but am feeling rather lost. Has anyone any experience of these techniques they could share?

[tilly]

sorry that should read speciation ...

[JI2002]

ICP-MS is usually used for metal analysis. You need to have a HPLC, IC or other chromatographic tools before ICP-MS for speciation analysis.

[msuk]

try this text?


Mass spectrometry of inorganic, coordination and organometallic compounds
/ William Henderson & J. Scott McIndoe.

ISBN 0-470-85015-9

[tilly]

thanks for replies,
I'll try to order the book from the library and see if i can make sense of it.

[sindhu]

ICP-MS is best suited for Inorganic MS analysis. Better you do Ion Chromatography before analysis

[Patrik Appelblad]

Another viable alternative would be to use HILIC coupled with ICP-MS.
Recently there has been papers published on this new combination of analytical techniques.

Hydrophilic Interaction Liquid Chromatography (HILIC) Coupled to Inductively Coupled Plasma Mass Spectrometry (ICPMS) utilizing a Mobile Phase with a Low-Volatile Organic Modifier for the Determination of Cisplatin, and its Monohydrolyzed Metabolite
Y. Nygren, P. Hemström, C. Åstot, P. Naredi, E. Björn
J. Anal. At. Spectrom., 23 (2008) 948-954


Alternative Organic Solvents for HILIC Separation of Cisplatin Species with On-Line ICP-MS Detection
P. Hemström, Y. Nygren, E. Björn, K. Irgum
J. Sep. Sci., 31 (2008) 599-603